Lab

hs-CRP Testing

A single blood marker for systemic inflammation — the through-line connecting cardiovascular, metabolic, and aging risk.

What it does

A single blood marker for systemic inflammation — the through-line connecting cardiovascular, metabolic, and aging risk. Just don't draw it during an acute illness.

High-sensitivity CRP detects low-grade systemic inflammation below the threshold a standard CRP test would flag.

  • hs-CRP

What the evidence shows

Overall evidence strength: High certainty

Who it's for, who should skip

Anyone screening chronic inflammation. Draw it when well — it spikes with any acute inflammatory event, which would misread a chronic baseline. Target <1.0 mg/L, longevity target <0.5.

Running it

Measuring it

Retest hs-CRP — No guideline-based repeat cadence — confirm with two readings at least 2 weeks apart, averaged. Serial monitoring is not recommended..

Access & cost

Ordered as a lab test through the bloodwork lane.

Last reviewed 27 August 2026.