Thyroid Panel
TSH flags thyroid dysfunction that mimics fatigue, weight change, and mood issues.
What it does
TSH flags thyroid dysfunction that mimics fatigue, weight change, and mood issues. Cheap and definitive enough that guessing is unnecessary.
TSH is released by the pituitary in response to circulating thyroid hormone — it rises when thyroid output is low and falls when output is high, making it the standard first-line screen.
What the evidence shows
Overall evidence strength: High certainty
Who it's for, who should skip
Anyone with nonspecific fatigue, weight, or mood symptoms. Subclinical thyroid dysfunction is common and easily missed. Standard range 0.4–4.0 mIU/L.
Running it
Measuring it
Retest TSH — No guideline interval for asymptomatic adults — on levothyroxine, 4–8 weeks after a dose change, then yearly once stable..
Access & cost
Ordered as a lab test through the bloodwork lane.
Last reviewed 27 August 2026.